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Detailed Program
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Topic
Immuno-metabolism
Immunotherapy
Infections and immune responses
Innate Immunity
Neuro-immunology
Vaccination against pathogens and cancers
18/06/2025
19/06/2025
20/06/2025
08:30 - 10:00 |
Registration and welcome coffee
10:00 - 10:15 |
Opening ceremony
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10:15 - 11:00 |
Keynote Lecture - Kate Fitzgerald
10:15 - 11:00 | Balancing Act: DNA Sensing Pathways in Health and Disease
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Katherine A. Fitzgerald
- University of Massachusetts Chan Medical School, United States
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11:00 - 12:00 |
Session 1 : Innate immunity - Endorsed by InnaSCo
11:00 - 11:30 | Why so many ways to die?
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Vishva M. DIXIT
- Genentech, Inc., United States
11:30 - 11:45 | TLR4-Driven Macrophage Priming Regulates Thymic Size Through Enhanced Efferocytosis
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Andri Lemarquis
- City of Hope (COH), United States
11:45 - 12:00 | TLR7-9 ADAPTORS TASL AND TASL2 MEDIATE IRF5-DEPENDENT ANTIVIRAL RESPONSES AND AUTOIMMUNITY.
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Manuele Rebsamen
- Dpt. of Immunobiology, University of Lausanne, Switzerland
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12:00 - 12:15 |
Poster teaser 1&2
12:00 - 12:15 | SINGLE STRANDED DNA SENSING IS ASSOCIATED WITH ACTIVATION OF INFLAMMATORY AND DNA DAMAGE RESPONSES INDEPENDENTLY OF CANONICAL NUCLEIC ACID DETECTION PATHWAYS
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Roger-Junior Eloiflin
- IGMM, Université de Montpellier, CNRS, France
12:00 - 12:15 | NEUTROPHILS ARE THE EARLIEST INNATE SENSORS OF PRENEOPLASTIC MAMMARY EPITHELIAL CELLS
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Antoine DEBIESSE
- Centre de Recherche en Cancérologie de Lyon (CRCL), France
12:00 - 12:15 | SURVIVAL MECHANISMS OF TUMOR-ASSOCIATED NEUTROPHILS IN A MOUSE MODEL OF LUNG SQUAMOUS CELL CARCINOMA
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Abdullah Mayet
- Department of Molecular Biology, Université Libre de Bruxelles, Belgium
12:00 - 12:15 | APOPTOTIC CASPASES SILENCE SPONTANEOUS INNATE IMMUNE SIGNALS BY SPECIFICALLY CLEAVING ACTIVATED MITOCHONDRIAL ANTIVIRAL SIGNALING PROTEIN (MAVS)
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Pallab Chakraborty
- Faculty of Biology, University of Freiburg, Germany
12:00 - 12:15 | Crosslinking of Ly6a metabolically reprogram CD8 T cells for cancer immunotherapy.
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Avishai Maliah
- Tel Aviv University , Israel
12:00 - 12:15 | LIPID METABOLISM PROFILING OF DIFFUSE LARGE B-CELL LYMPHOMA CELLS PREDICTS SENSITIVITY TO FERROPTOSIS
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Véronique Baud
- Inserm, Université Paris Cité, NF-κB, Differentiation and Cancer, France
12:00 - 12:15 | Validation of new mTOR regulatory genes identified in a human NK cell CRISPR/Cas9 screen
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Emily Sible
- CIRI, Centre International de Recherche en Infectiologie, Univ. Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, France
12:00 - 14:00 |
Lunch and posters sessions 1 & 2
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14:00 - 15:45 |
Session 1 : Innate immunity - Endorsed by InnaSCo
14:00 - 14:30 | Microbial viability drives immunometabolic responses of macrophages
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Johan Garaude
- Mitochondrial Biology and Innate Immunity ImmunoConcEpT, University of Bordeaux, France
14:30 - 15:00 | Agents of Progression and Protection: How Innate Immunity Shapes Metastasis
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Mikala EGEBLAD
- John Hopkins University, United States
15:00 - 15:30 | Functional analysis of natural variants in diagnosis of autoinflammatory diseases, and understanding of inflammasome regulation
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Bénédicte PY
- Centre International de Recherche en Infectiologie , France
15:45 - 16:15 |
Coffee Break
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16:15 - 18:15 |
Session 2 : Immuno-metabolism
16:45 - 17:00 | TIGAR: A KEY METABOLIC MODULATOR GOVERNING CD4 T CELL METABOLISM AND FATE
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Elpida Bokou Gianneli
- Université de Montréal, 2900, Bd Édouard-Montpetit, Montréal (Qc) H3T 1J4, Centre de Recherche Hôpital Maisonneuve Rosemont, 5415, Bd de l'Assomption Montréal (Qc) H1T 2M4, Canada
17:00 - 17:30 | Use of carbon sources in human and murine natural killer cells: variation on a common theme.
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Antoine Marçais
- Centre International de Recherche en Infectiologie , France
17:30 - 17:45 | EXPLORING TCR-DEPENDENT METABOLIC IMPRINTING OF ANTI-VIRAL T CELL RESPONSES
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Hannah Bollons
- University of Birmingham, United Kingdom
17:45 - 18:15 | Increasing CAR T cell persistence instructed by basic immuno-metabolic principles
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Christopher Hess
- University of Basel, Switzerland
18:15 - 21:00 |
Welcome cocktail with gourmet light bites and poster sessions1&2
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09:00 - 10:30 |
Session 3 : Immunotherapy and clinics
09:00 - 09:30 | Diagnosis of infectious and inflammatory diseases by RNA molecular signatures: Towards a Molecular Taxonomy of infectious and inflammatory diseases.
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Michael Levin
- Imperial College London, United Kingdom
09:30 - 09:45 | DPP9-mediated Inflammasome Repression Protects Against Checkpoint Inhibitor Pneumonitis
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Ricky Brewer
- Yale University, United States
09:45 - 10:15 | Overcoming Resistance to PD-1 Checkpoint Blockade for Cancer Immunotherapy
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Arlene H. Sharpe
- Harvard Medical School, United States
10:15 - 10:30 | Effector T lymphocytes can initiate spontaneous cancers
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valentin Thevin
- CRCL, France
10:30 - 11:00 |
Coffee break
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11:00 - 12:30 |
Session 3 : Immunotherapy and clinics
11:00 - 11:30 | Decoding the mode of action of tumor immunotherapies in vivo
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Philippe Bousso
- Institut Pasteur , France
11:30 - 11:45 | Age is a critical driver of the pediatric tumour microenvironment and the response to immunotherapy
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Willem Joost Lesterhuis
- The Kids Research Institute Australia, Australia
11:45 - 12:00 | Tumor specific regulation of T cell exhaustion can be targeted for immunotherapy
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Gregory Verdeil
- Department of Oncology, UNIL CHUV, University of Lausanne, Switzerland
12:00 - 12:30 | Regulation of T-cell responses to cancer by the NF-kappaB family of transcription factors.
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Yenkel GRINBERG-BLEYER
- Cancer Research Center of Lyon, France
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12:30 - 12:45 |
Poster teaser 3&4
12:30 - 12:45 | ROLE OF INFLAMMATION AND TRANSCRIPTION FACTOR FOXO1 ON T-CELL EXHAUSTION IN THE COURSE OF ANTI-TUMOR IMMUNE RESPONSES
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Amélie Lombès
- Institut Cochin, INSERM U1016, CNRS 8104, Université Paris Cité, France
12:30 - 12:45 | NON-CANONICAL TRANSLATION OF ONCOGENES IN CANCER CELLS GENERATES SHARED AND IMMUNOGENIC NEOEPITOPES
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Anaëlle Bolon
- Centre de Recherche en Cancérologie de Lyon, UMR INSERM U1052 CNRS 5286 Université Claude Bernard Lyon 1 Centre Léon Bérard, France
12:30 - 12:45 | Disruption of RINF gene (also known as CXXC5) improves persistence and antitumoral efficacy of CAR T cell therapy
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Dongjie An
- Université Paris Cité, Institut Cochin, INSERM, CNRS, Equipe Labélisée Ligue Nationale Contre le Cancer , France
12:30 - 12:45 | NF-κB2 Transcription Factor Drives CD8⁺ T-Cell Antitumor Functions
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Khaled Bouherrou
- Cancer Research Center of Lyon (CRCL) - Inserm U1052, France
12:30 - 12:45 | IKKbeta is an intrinsic immune checkpoint in melanoma cells and predicts patients’ response to immunotherapy
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Toby Lawrence
- Centre d'Immunologie Marseille-Luminy, INSERM, France
12:30 - 12:45 | The role of myeloid cells in skull-to-brain axis & neuroinflammation
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Elisa Eme-Scolan
- Centre d'Immunologie de Marseille Luminy, France
12:30 - 12:45 | HTLV-1-associated cancer induces neuro-immune dysregulation correlated with disease severity
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Fernando Yuri Nery do Vale
- Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo (USP), Brazil
12:45 - 14:30 |
Lunch and posters sessions 3&4
13:30 - 14:15 |
Meet the editors
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14:30 - 15:45 |
Session 4 : Neuro-Immunology
14:30 - 15:00 | Brain borders take center stage: role of meningeal macrophages in neurocognition and neuroinflammation
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Réjane Rua
- Centre d'Immunologie de Marseille-Luminy (CIML), France
15:00 - 15:15 | Extrafollicular generation of antibody-secreting cells in highly infiltrated ovarian tumors
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Gabriel Chemin
- Cancer Research Center of Lyon (CRCL), France
15:15 - 15:45 | Scratching exaggerates allergic inflammation and augments host defense via neurogenic mast cell activation
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Dan KAPLAN
- Departments of Dermatology and Immunology, University of Pittsburgh, United States
15:45 - 16:15 |
Coffee Break
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16:15 - 17:00 |
Keynote Lecture -Henrique Veiga Fernandes
16:15 - 17:00 | Neuroimmune ecosystems in health and disease
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Henrique Veiga-Fernandes
- Champalimaud Foundation, Portugal
19:30 - 00:00 |
Congress party
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09:00 - 10:15 |
Session 5 : Vaccination against infection and cancer
09:00 - 09:30 | Replication of human seasonal coronavirus HKU1 and antiviral immune responses
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Olivier SCHWARTZ
- Virus & Immunity Unit, Institut Pasteur, France
09:30 - 10:00 | Decoding the mode of action of tumor immunotherapies in vivo
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Philippe Bousso
- Institut Pasteur , France
10:00 - 10:15 | A cytomegalovirus-based vaccine against Lassa virus in the Mastomys natalensis rodent reservoir
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Kyle Rosenke
- National Institutes of Allergy and Infectious Disease, United States
10:15 - 10:45 |
Coffee break
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10:45 - 11:45 |
Session 5 : Vaccination against infection and cancer
10:45 - 11:15 | Preclinical development of ErVac01, a viral-vectored vaccine encoding tumor epitopes derived from endogenous retrovirus sequences
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Paola Bonaventura
- ErVimmune, France - Centre de Recherche en Cancérologie de Lyon (CRCL), France
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11:45 - 12:00 |
Poster teaser 5&6
11:45 - 12:00 | DEVELOPMENT OF A NEW THERAPEUTIC VACCINATION STRATEGY BASED ON LONG ARTIFICIAL SYNTHETIC PEPTIDES IN MELANOMA.
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Amélie GUIHO
- Immunology and New Concepts in ImmunoTherapy, INCIT, Nantes Université, Université d'Angers, Inserm, France
11:45 - 12:00 | Effect of fever-range hyperthermia on the humoral immune response
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Marie Le Borgne
- INSERM U1148 “Laboratory for Vascular Translational Science”, France
11:45 - 12:00 | Vaccination prevents immune suppression and tissue disruption in LCMV-induced Post-Acute Syndromes
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Paula Cebollada Rica
- Universitat Pompeu Fabra, Spain
11:45 - 12:00 | HLA-E-dependent adaptations of NKG2A+ and NKG2C+ NK cells in people living with HIV
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Emma Beaumont
- Institut Pasteur, Université Paris-Cité, HIV Inflammation & Viral Persistences Unit, France
11:45 - 12:00 | Role of the inflammasome pathway in the expansion and functions of regulatory plasma cells during sepsis
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Clara Vigneron
- Equipe Inflammasome NLRP3 et réponse immunitaire au sepsis - Centre International de Recherche en Infectiologie, France
11:45 - 12:00 | CYLD PROTEOLYSIS BY CASPASE-3, A CHECKPOINT TO BALANCE INFLAMMATION DURING MITOCHONDRIAL APOPTOSIS?
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Yanis Macé
- SOAP Team, CRCI2NA, INSERM U1307, CNRS U6075, Nantes Université, Université d’Angers, France
11:45 - 12:00 | Critical COVID-19 unveils the link between viral particle blood dissemination and prolonged Type I Interferon
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William Mouton
- Hospices Civils de Lyon, France - Centre international de recherche en infectiologie - CIRI, France
12:00 - 14:00 |
Lunch and posters sessions 5&6
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14:00 - 15:45 |
Session 6 : Infections and immune responses
14:00 - 14:30 | Immune responses to persistent viral infections
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Annette Oxenius
- Institute of Microbiology, ETH Zurich, Switzerland
14:30 - 14:45 | Tlr7 expression from the inactive X chromosome in female B cells contributes to the germinal center response to virus-like particles (pathogen-like COVID-19 vaccine)
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Mélissa Nieucel
- Infinity Toulouse, France
14:45 - 15:15 | Memory CD8 T Cells: Quantity, Quality, and Location
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David MASOPUST
- University Minnesota, United States
15:15 - 15:45 | Regulatory Plasma Cells and rRNA Epitranscriptomic Modifications as Novel Mechanisms of Sepsis-Induced T Cell Dysfunction
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Fabienne VENET
- Centre International de Recherche en Infectiologie , France - Centre de recherche en Cancerologie de Lyon, France
15:45 - 16:15 |
Coffee Break
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16:15 - 17:00 |
Session 6 : Infections and immune responses
16:15 - 16:30 |
Non-AUG upstream open reading frame translation from viral transcripts elicits specific T cell immune responses in people living with HIV-1
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Emiliano RICCI
- LBMC - ENS de Lyon, France
16:30 - 17:00 | Breakthrough in RSV prevention
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Louis BONT
- UMC Utrecht, Netherlands
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17:00 - 17:45 |
Keynote Lecture - Vijay Kuchroo
17:00 - 17:45 | Neuroimmune interactions regulate T cell fate and the development of type II immunity
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Vijay K. Kuchroo
- Brighten and Women’ hospital, Harvard Medical School, United States
17:45 - 18:15 |
Poster prizes and closing ceremony
LieutestTT
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